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Patient education

Acute Kidney Injury (AKI)

Acute kidney injury means the kidneys lose function suddenly — over hours or days — rather than gradually. It is usually detected as a rapid rise in creatinine or a fall in urine output. Treated early, kidney function often recovers.

Sudden onsetOften reversibleNeeds prompt attention
Illustration of a kidney with a rising alert arrow, an IV drip and a stopwatch

The basics

What happens in AKI?

In AKI the kidneys can no longer clear waste and balance fluid properly. Because the change is fast, waste products and fluid can build up quickly.

Creatinine and urea rise quickly

Urine output may fall (or stay normal)

Potassium and acid can build up

Fluid may collect in the legs or lungs

Blood pressure can swing high or low

Often found on a routine blood test

What can cause AKI?

Causes are grouped by where the problem lies — reduced blood flow to the kidney, damage within the kidney itself, or an obstruction to urine flow.

Dehydration, vomiting or diarrhoea
Severe infection or sepsis
Painkillers, some antibiotics, contrast dye
Heart or liver failure
Blockage from stones or an enlarged prostate
Major surgery, bleeding or burns

Recognising it

AKI can be quiet at first

Some people feel completely well and AKI is picked up only on a blood test. When symptoms do appear, they can develop rapidly.

If you are unwell with vomiting, diarrhoea or fever and are taking blood pressure, diabetes or diuretic medicines, ask your doctor whether any should be paused — this is often called sick-day guidance.

Possible symptoms

  • Passing much less urine than usual
  • Swelling of the legs, ankles or face
  • Tiredness and confusion
  • Nausea or vomiting
  • Breathlessness
  • Chest discomfort

Diagnosis

How is AKI assessed?

Blood tests

Creatinine, urea, electrolytes and acid-base status show how severe the injury is and how quickly it is changing.

Urine tests

Urine is examined for protein, blood, cells and casts — these clues help distinguish between the possible causes.

Ultrasound

A kidney ultrasound checks kidney size and looks for any blockage to urine flow, which can often be relieved quickly.

Treatment

How AKI is managed

There is no single pill for AKI. Treatment means correcting the cause and supporting the kidneys while they recover.

  1. 01

    Treat the underlying cause

    Infection is treated, bleeding is controlled, and any obstruction to urine flow is relieved. This is the single most important step.

  2. 02

    Restore fluid balance

    Fluids are given if you are dehydrated, or restricted and removed if fluid has overloaded the body. Balance is monitored closely.

  3. 03

    Stop kidney-harming medicines

    Painkillers such as ibuprofen and diclofenac, some antibiotics and certain blood pressure medicines may be paused or dose-adjusted.

  4. 04

    Correct electrolytes

    High potassium and acid build-up are treated promptly because they can affect the heart.

  5. 05

    Dialysis, if needed

    A minority of people need temporary dialysis while the kidneys recover. This is usually short-term, not lifelong.

  6. 06

    Follow up afterwards

    Kidney function should be rechecked after recovery. An episode of AKI raises the future risk of chronic kidney disease, so ongoing monitoring matters.

When should you seek medical help?

Contact your doctor if you have

  • A marked reduction in urine
  • New or rapidly increasing swelling
  • Ongoing vomiting or diarrhoea
  • A recent blood test showing a rise in creatinine
  • Fever with feeling very unwell

Seek urgent medical attention for

Severe breathlessness, chest pain, confusion or drowsiness, or passing almost no urine at all.

The most important message

AKI is a warning signal, not a life sentence. Found and treated early, kidney function frequently recovers — and follow-up protects you afterwards.

How fast your creatinine changed
Your urine output
Medicines to pause when unwell
A repeat kidney test after recovery

Ask your doctor to recheck your kidney function after an AKI episode.

If you are concerned about your kidney health, speak with a qualified healthcare professional. This information is for patient education and does not replace individual medical advice.